Scoperto un gene che rende regolare il ritmo sonno-veglia – Medicina

By On Nov 24, 2021

- Advertisement -

(ANSA) – ROMA, 24 NOV – La vita è organizzata sulle 24 ore.

Al centro di questo ritmo regolare c’è l’orologio circadiano, un
segnatempo presente praticamente in ogni tipo di organo, tessuto
e cellula. Quando un orologio va storto, possono verificarsi
disturbi del sonno o una varietà di malattie. Una scoperta della
Northwestern University potrebbe aiutare a capire come questo
orologio sia collegato ai cicli giornalieri: è stato infatti
identificato un nuovo gene, chiamato Tango10, che è fondamentale
per i ritmi quotidiani.

Questo gene è coinvolto in un percorso molecolare attraverso il
quale l’orologio circadiano centrale (gli “ingranaggi”)
controlla l’output cellulare dell’orologio (le “lancette”) per
controllare i cicli sonno-veglia quotidiani. Sebbene la ricerca
sia stata condotta utilizzando il moscerino della frutta
Drosophila melanogaster, i risultati, secondo gli studiosi,
hanno implicazioni per gli esseri umani.

La conoscenza di come funziona questo percorso potrebbe portare
infatti a terapie per aiutare a trattare i problemi del sonno e
potrebbe far luce sulle malattie umane legate all’orologio
circadiano, come la depressione, le malattie neurodegenerative e
quelle metaboliche. Quando gli studiosi hanno eliminato questo
gene, la mosca ha perso il suo normale ritmo di comportamento
sulle 24 ore. Alcune correnti di potassio sono state ridotte e
probabilmente hanno portato a neuroni iperattivi e hanno
contribuito a una perdita del ritmo regolare. In condizioni
normali, invece i livelli della proteina Tango10 salgono e
diminuiscono con il ritmo circadiano. Il lavoro è stato
pubblicato sulla rivista scientifica Pnas. (ANSA).

Ottieni il codice embed
</p> </div> <p> <style><![CDATA[<![CDATA[ .pp-lbl{ background: #7ec4d8; color: #fff; font-size: 13px; line-height: 18px; text-transform: uppercase; margin: 0 0 1px; padding: 9px 0 9px 15px; width:100%!important; } .adv-static{margin-bottom:20px;} ]]]]><![CDATA[>]]></style> <p></p> <p></p> <style><![CDATA[<![CDATA[ .template-shown {position: relative;} .template-shown::before {content: "";position: absolute;bottom: 100%;left: 0;right: 0;height: 100px;background-image: linear-gradient(to top, #ffffff 0%, #ffffff 0%, rgba(255, 255, 255, 0) 100%);} ]]]]><![CDATA[>]]></style> <p> </p></div> <p><br /> <br /><a href="https://www.ansa.it/canale_saluteebenessere/notizie/medicina/2021/11/24/scoperto-un-gene-che-rende-regolare-il-ritmo-sonno-veglia_7389c3d5-ba59-4092-9b4b-0957ca4aba88.html">www.ansa.it </a>2021-11-24 11:44:27 </p> </div> <div class="entry-terms post-tags clearfix "> <span class="terms-label"><i class="fa fa-tags"></i></span> <a href="https://lombardiasalute.com/tag/che/" rel="tag">Che</a><a href="https://lombardiasalute.com/tag/ciclo/" rel="tag">ciclo</a><a href="https://lombardiasalute.com/tag/disturbo-del-sonno/" rel="tag">disturbo del sonno</a><a href="https://lombardiasalute.com/tag/gene/" rel="tag">gene</a><a href="https://lombardiasalute.com/tag/implicazione/" rel="tag">implicazione</a><a href="https://lombardiasalute.com/tag/malattia/" rel="tag">malattia</a><a href="https://lombardiasalute.com/tag/medicina/" rel="tag">Medicina</a><a href="https://lombardiasalute.com/tag/mosca/" rel="tag">Mosca</a> </div> <div class="post-share single-post-share bottom-share clearfix style-4"> <div class="post-share-btn-group"> <span class="views post-share-btn post-share-btn-views rank-default" data-bpv-post="17256"><i class="bf-icon fa fa-eye"></i> <b class="number">38</b></span> </div> <div class="share-handler-wrap "> <span class="share-handler post-share-btn rank-default"> <i class="bf-icon fa fa-share-alt"></i> <b class="text">Share</b> </span> <span class="social-item facebook has-title"><a href="https://www.facebook.com/sharer.php?u=https%3A%2F%2Flombardiasalute.com%2F2021%2F11%2F24%2Fscoperto-un-gene-che-rende-regolare-il-ritmo-sonno-veglia-medicina%2F" target="_blank" rel="nofollow noreferrer" class="bs-button-el" onclick="window.open(this.href, 'share-facebook','left=50,top=50,width=600,height=320,toolbar=0'); return false;"><span class="icon"><i class="bf-icon fa fa-facebook"></i></span><span class="item-title">Facebook</span></a></span><span class="social-item twitter has-title"><a href="https://twitter.com/share?text=Scoperto un gene che rende regolare il ritmo sonno-veglia – Medicina @#&url=https%3A%2F%2Flombardiasalute.com%2F2021%2F11%2F24%2Fscoperto-un-gene-che-rende-regolare-il-ritmo-sonno-veglia-medicina%2F" target="_blank" rel="nofollow noreferrer" class="bs-button-el" onclick="window.open(this.href, 'share-twitter','left=50,top=50,width=600,height=320,toolbar=0'); return false;"><span class="icon"><i class="bf-icon fa fa-twitter"></i></span><span class="item-title">Twitter</span></a></span><span class="social-item google_plus has-title"><a href="https://plus.google.com/share?url=https%3A%2F%2Flombardiasalute.com%2F2021%2F11%2F24%2Fscoperto-un-gene-che-rende-regolare-il-ritmo-sonno-veglia-medicina%2F" target="_blank" rel="nofollow noreferrer" class="bs-button-el" onclick="window.open(this.href, 'share-google_plus','left=50,top=50,width=600,height=320,toolbar=0'); return false;"><span class="icon"><i class="bf-icon fa fa-google"></i></span><span class="item-title">Google+</span></a></span><span class="social-item reddit has-title"><a href="https://reddit.com/submit?url=https%3A%2F%2Flombardiasalute.com%2F2021%2F11%2F24%2Fscoperto-un-gene-che-rende-regolare-il-ritmo-sonno-veglia-medicina%2F&title=Scoperto un gene che rende regolare il ritmo sonno-veglia – Medicina" target="_blank" rel="nofollow noreferrer" class="bs-button-el" onclick="window.open(this.href, 'share-reddit','left=50,top=50,width=600,height=320,toolbar=0'); return false;"><span class="icon"><i class="bf-icon fa fa-reddit-alien"></i></span><span class="item-title">ReddIt</span></a></span><span class="social-item whatsapp has-title"><a href="whatsapp://send?text=Scoperto un gene che rende regolare il ritmo sonno-veglia – Medicina %0A%0A https%3A%2F%2Flombardiasalute.com%2F2021%2F11%2F24%2Fscoperto-un-gene-che-rende-regolare-il-ritmo-sonno-veglia-medicina%2F" target="_blank" rel="nofollow noreferrer" class="bs-button-el" onclick="window.open(this.href, 'share-whatsapp','left=50,top=50,width=600,height=320,toolbar=0'); return false;"><span class="icon"><i class="bf-icon fa fa-whatsapp"></i></span><span class="item-title">WhatsApp</span></a></span><span class="social-item pinterest has-title"><a href="https://pinterest.com/pin/create/button/?url=https%3A%2F%2Flombardiasalute.com%2F2021%2F11%2F24%2Fscoperto-un-gene-che-rende-regolare-il-ritmo-sonno-veglia-medicina%2F&media=https://lombardiasalute.com/wp-content/uploads/2021/11/6d558f45d2d88c53d5eb6a8d5e36f2a8.jpg&description=Scoperto un gene che rende regolare il ritmo sonno-veglia – Medicina" target="_blank" rel="nofollow noreferrer" class="bs-button-el" onclick="window.open(this.href, 'share-pinterest','left=50,top=50,width=600,height=320,toolbar=0'); return false;"><span class="icon"><i class="bf-icon fa fa-pinterest"></i></span><span class="item-title">Pinterest</span></a></span><span class="social-item email has-title"><a href="mailto:?subject=Scoperto un gene che rende regolare il ritmo sonno-veglia – Medicina&body=https%3A%2F%2Flombardiasalute.com%2F2021%2F11%2F24%2Fscoperto-un-gene-che-rende-regolare-il-ritmo-sonno-veglia-medicina%2F" target="_blank" rel="nofollow noreferrer" class="bs-button-el" onclick="window.open(this.href, 'share-email','left=50,top=50,width=600,height=320,toolbar=0'); return false;"><span class="icon"><i class="bf-icon fa fa-envelope-open"></i></span><span class="item-title">E-mail</span></a></span></div> </div> </article> <section class="post-author clearfix"> <a href="https://lombardiasalute.com/author/" title="Sfoglia Autore Articoli"> <span class="post-author-avatar" itemprop="image"></span> </a> <div class="author-title heading-typo"> <a class="post-author-url" href="https://lombardiasalute.com/author/"><span class="post-author-name"></span></a> <span class="title-counts">0 posts</span> <span class="title-counts">0 comments</span> </div> <div class="author-links"> </div> <div class="post-author-bio" itemprop="description"> </div> </section> <section class="next-prev-post clearfix"> <div class="prev-post"> <p class="pre-title heading-typo"><i class="fa fa-arrow-left"></i> Prev Post </p> <p class="title heading-typo"><a href="https://lombardiasalute.com/2021/11/24/sondaggio-l88-degli-italiani-non-li-conosce-ma-potrebbero-curare-piu-persone/" rel="prev">Sondaggio, l’88% degli italiani non li conosce, ma potrebbero curare più persone</a></p> </div> <div class="next-post"> <p class="pre-title heading-typo">Next Post <i class="fa fa-arrow-right"></i></p> <p class="title heading-typo"><a href="https://lombardiasalute.com/2021/11/24/salute-scarsa-idratazione-rende-piu-sensibili-al-dolore-lombardia/" rel="next">Salute: scarsa idratazione rende più sensibili al dolore – Lombardia</a></p> </div> </section> </div> <div class="post-related"> <div class="section-heading sh-t7 sh-s1 multi-tab"> <a href="#relatedposts_833533976_1" class="main-link active" data-toggle="tab"> <span class="h-text related-posts-heading">Potrebbe piacerti anche</span> </a> <a href="#relatedposts_833533976_2" class="other-link" data-toggle="tab" data-deferred-event="shown.bs.tab" data-deferred-init="relatedposts_833533976_2"> <span class="h-text related-posts-heading">Altri di autore</span> </a> </div> <div class="tab-content"> <div class="tab-pane bs-tab-anim bs-tab-animated active" id="relatedposts_833533976_1"> <div class="bs-pagination-wrapper main-term-none next_prev "> <div class="listing listing-thumbnail listing-tb-2 clearfix scolumns-3 simple-grid include-last-mobile"> <div class="post-44056 type-post format-standard has-post-thumbnail listing-item listing-item-thumbnail listing-item-tb-2 main-term-951"> <div class="item-inner clearfix"> <div class="featured featured-type-featured-image"> <div class="term-badges floated"><span class="term-badge term-951"><a href="https://lombardiasalute.com/category/celebrity/">Celebrity</a></span></div> <a title="Parte la nuova Aifa, priorità carenze farmaci e contro fake – Sanità" data-src="https://lombardiasalute.com/wp-content/uploads/2024/04/85c7078021a3d25693d1ef50aa47cc22-210x136.jpg" data-bs-srcset="{"baseurl":"https:\/\/lombardiasalute.com\/wp-content\/uploads\/2024\/04\/","sizes":{"86":"85c7078021a3d25693d1ef50aa47cc22-86x64.jpg","210":"85c7078021a3d25693d1ef50aa47cc22-210x136.jpg","279":"85c7078021a3d25693d1ef50aa47cc22-279x220.jpg","357":"85c7078021a3d25693d1ef50aa47cc22-357x210.jpg","700":"85c7078021a3d25693d1ef50aa47cc22.jpg"}}" class="img-holder" href="https://lombardiasalute.com/2024/04/23/parte-la-nuova-aifa-priorita-carenze-farmaci-e-contro-fake-sanita/"></a> </div> <p class="title"> <a class="post-url" href="https://lombardiasalute.com/2024/04/23/parte-la-nuova-aifa-priorita-carenze-farmaci-e-contro-fake-sanita/" title="Parte la nuova Aifa, priorità carenze farmaci e contro fake – Sanità"> <span class="post-title"> Parte la nuova Aifa, priorità carenze farmaci e contro fake – Sanità </span> </a> </p></div> </div > <div class="post-44048 type-post format-standard has-post-thumbnail listing-item listing-item-thumbnail listing-item-tb-2 main-term-951"> <div class="item-inner clearfix"> <div class="featured featured-type-featured-image"> <div class="term-badges floated"><span class="term-badge term-951"><a href="https://lombardiasalute.com/category/celebrity/">Celebrity</a></span></div> <a title="Cortellesi presenta Aisha la mascotte all’ospedale del Cuore – Bambini news" data-src="https://lombardiasalute.com/wp-content/uploads/2024/04/0cf2518ee91a552619b0be07e176da13-210x136.jpg" data-bs-srcset="{"baseurl":"https:\/\/lombardiasalute.com\/wp-content\/uploads\/2024\/04\/","sizes":{"86":"0cf2518ee91a552619b0be07e176da13-86x64.jpg","210":"0cf2518ee91a552619b0be07e176da13-210x136.jpg","279":"0cf2518ee91a552619b0be07e176da13-279x220.jpg","357":"0cf2518ee91a552619b0be07e176da13-357x210.jpg","700":"0cf2518ee91a552619b0be07e176da13.jpg"}}" class="img-holder" href="https://lombardiasalute.com/2024/04/23/cortellesi-presenta-aisha-la-mascotte-allospedale-del-cuore-bambini-news/"></a> </div> <p class="title"> <a class="post-url" href="https://lombardiasalute.com/2024/04/23/cortellesi-presenta-aisha-la-mascotte-allospedale-del-cuore-bambini-news/" title="Cortellesi presenta Aisha la mascotte all’ospedale del Cuore – Bambini news"> <span class="post-title"> Cortellesi presenta Aisha la mascotte all’ospedale del Cuore – Bambini… </span> </a> </p></div> </div > <div class="post-44038 type-post format-standard has-post-thumbnail listing-item listing-item-thumbnail listing-item-tb-2 main-term-951"> <div class="item-inner clearfix"> <div class="featured featured-type-featured-image"> <div class="term-badges floated"><span class="term-badge term-951"><a href="https://lombardiasalute.com/category/celebrity/">Celebrity</a></span></div> <a title="Tumore al seno, all’Int studio sull’efficacia della restrizione calorica – Focus Tumo…" data-src="https://lombardiasalute.com/wp-content/uploads/2024/04/caaddc9fc2675f333c04337317990e6a-210x136.jpg" data-bs-srcset="{"baseurl":"https:\/\/lombardiasalute.com\/wp-content\/uploads\/2024\/04\/","sizes":{"86":"caaddc9fc2675f333c04337317990e6a-86x64.jpg","210":"caaddc9fc2675f333c04337317990e6a-210x136.jpg","279":"caaddc9fc2675f333c04337317990e6a-279x220.jpg","357":"caaddc9fc2675f333c04337317990e6a-357x210.jpg","700":"caaddc9fc2675f333c04337317990e6a.jpg"}}" class="img-holder" href="https://lombardiasalute.com/2024/04/23/tumore-al-seno-allint-studio-sullefficacia-della-restrizione-calorica-focus-tumo/"></a> </div> <p class="title"> <a class="post-url" href="https://lombardiasalute.com/2024/04/23/tumore-al-seno-allint-studio-sullefficacia-della-restrizione-calorica-focus-tumo/" title="Tumore al seno, all’Int studio sull’efficacia della restrizione calorica – Focus Tumo…"> <span class="post-title"> Tumore al seno, all’Int studio sull’efficacia della restrizione calorica… </span> </a> </p></div> </div > <div class="post-44029 type-post format-standard has-post-thumbnail listing-item listing-item-thumbnail listing-item-tb-2 main-term-951"> <div class="item-inner clearfix"> <div class="featured featured-type-featured-image"> <div class="term-badges floated"><span class="term-badge term-951"><a href="https://lombardiasalute.com/category/celebrity/">Celebrity</a></span></div> <a title="Boom del morbillo nella regione europea Oms, i casi saliti 60 volte" data-src="https://lombardiasalute.com/wp-content/uploads/2024/04/a554a465a135719dc52ee7971dcdaa67-210x136.jpg" data-bs-srcset="{"baseurl":"https:\/\/lombardiasalute.com\/wp-content\/uploads\/2024\/04\/","sizes":{"86":"a554a465a135719dc52ee7971dcdaa67-86x64.jpg","210":"a554a465a135719dc52ee7971dcdaa67-210x136.jpg","279":"a554a465a135719dc52ee7971dcdaa67-279x220.jpg","357":"a554a465a135719dc52ee7971dcdaa67-357x210.jpg","700":"a554a465a135719dc52ee7971dcdaa67.jpg"}}" class="img-holder" href="https://lombardiasalute.com/2024/04/22/boom-del-morbillo-nella-regione-europea-oms-i-casi-saliti-60-volte/"></a> </div> <p class="title"> <a class="post-url" href="https://lombardiasalute.com/2024/04/22/boom-del-morbillo-nella-regione-europea-oms-i-casi-saliti-60-volte/" title="Boom del morbillo nella regione europea Oms, i casi saliti 60 volte"> <span class="post-title"> Boom del morbillo nella regione europea Oms, i casi saliti 60 volte </span> </a> </p></div> </div > </div> </div><div class="bs-pagination bs-ajax-pagination next_prev main-term-none clearfix"> <script>var bs_ajax_paginate_1787090290 = '{"query":{"paginate":"next_prev","count":4,"post_type":"post","posts_per_page":4,"post__not_in":[17256],"ignore_sticky_posts":1,"post_status":["publish","private"],"category__in":[951],"remove_duplicates_ids":"17256","_layout":{"state":"1|1|0","page":"2-col-right"}},"type":"wp_query","view":"Publisher::fetch_related_posts","current_page":1,"ajax_url":"\/wp-admin\/admin-ajax.php","remove_duplicates":"1","remove_duplicates_ids":"17256","paginate":"next_prev","_layout":{"state":"1|1|0","page":"2-col-right"},"_bs_pagin_token":"ea14d99"}';</script> <a class="btn-bs-pagination prev disabled" rel="prev" data-id="1787090290" title="Precedente"> <i class="fa fa-angle-left" aria-hidden="true"></i> Prev </a> <a rel="next" class="btn-bs-pagination next" data-id="1787090290" title="Il prossimo"> Next <i class="fa fa-angle-right" aria-hidden="true"></i> </a> </div> </div> <div class="tab-pane bs-tab-anim bs-tab-animated bs-deferred-container" id="relatedposts_833533976_2"> <div class="bs-pagination-wrapper main-term-none next_prev "> <div class="bs-deferred-load-wrapper" id="bsd_relatedposts_833533976_2"> <script>var bs_deferred_loading_bsd_relatedposts_833533976_2 = '{"query":{"paginate":"next_prev","count":4,"author":"","post_type":"post","_layout":{"state":"1|1|0","page":"2-col-right"}},"type":"wp_query","view":"Publisher::fetch_other_related_posts","current_page":1,"ajax_url":"\/wp-admin\/admin-ajax.php","remove_duplicates":"0","paginate":"next_prev","_layout":{"state":"1|1|0","page":"2-col-right"},"_bs_pagin_token":"716575c"}';</script> </div> </div> </div> </div> </div> </div> <div class="col-sm-4 sidebar-column sidebar-column-primary"> <aside id="sidebar-primary-sidebar" class="sidebar" role="complementary" aria-label="Primary Sidebar Sidebar" itemscope="itemscope" itemtype="https://schema.org/WPSideBar"> </aside> </div> </div> </div> </main> </div> <footer id="site-footer" class="site-footer full-width"> <div class="copy-footer"> <div class="content-wrap"> <div class="container"> <div class="row"> <div class="col-lg-12"> <div id="menu-footer" class="menu footer-menu-wrapper" role="navigation" itemscope="itemscope" itemtype="https://schema.org/SiteNavigationElement"> <nav class="footer-menu-container"> <ul id="footer-navigation" class="footer-menu menu clearfix"> <li id="menu-item-648" class="menu-item menu-item-type-post_type menu-item-object-page better-anim-fade menu-item-648"><a href="https://lombardiasalute.com/contact-us/">Contact Us</a></li> <li id="menu-item-650" class="menu-item menu-item-type-post_type menu-item-object-page better-anim-fade menu-item-650"><a href="https://lombardiasalute.com/cookie-privacy-policy/">Cookie Policy</a></li> <li id="menu-item-651" class="menu-item menu-item-type-post_type menu-item-object-page better-anim-fade menu-item-651"><a href="https://lombardiasalute.com/privacy-policy-2/">Privacy Policy</a></li> <li id="menu-item-652" class="menu-item menu-item-type-post_type menu-item-object-page better-anim-fade menu-item-652"><a href="https://lombardiasalute.com/terms-of-use-2/">Terms of Use</a></li> <li id="menu-item-649" class="menu-item menu-item-type-post_type menu-item-object-page better-anim-fade menu-item-649"><a href="https://lombardiasalute.com/dmca/">DMCA</a></li> </ul> </nav> </div> </div> </div> <div class="row footer-copy-row"> <div class="copy-1 col-lg-6 col-md-6 col-sm-6 col-xs-12"> © 2024 - Lombardia Salute. All Rights Reserved. </div> <div class="copy-2 col-lg-6 col-md-6 col-sm-6 col-xs-12"> Website Design: <a href="http://betterstudio.com/">BetterStudio</a> </div> </div> </div> </div> </div> </footer> </div> <div class="bs-wrap-gdpr-law bs-wrap-gdpr-law-close"> <div class="bs-gdpr-law"> <p> This website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish. <a class="bs-gdpr-accept" href="#" data-cookie="show">Accept</a> <a class="bs-gdpr-more" href="#">Read More</a> </p> </div> </div> <span class="back-top"><i class="fa fa-arrow-up"></i></span> <style type="text/css" media="print"> * { display: none !important; } body, html { display: block !important; } #cpp-print-disabled { top: 0; left: 0; color: #111; width: 100%; height: 100%; min-height: 400px; z-index: 9999; position: fixed; font-size: 30px; text-align: center; background: #fcfcfc; padding-top: 200px; display: block !important; } </style> <div id="cpp-print-disabled" style="display: none;"> You cannot print contents of this website. </div> <script type="text/javascript" id="publisher-theme-pagination-js-extra"> /* <![CDATA[ */ var bs_pagination_loc = {"loading":"<div class=\"bs-loading\"><div><\/div><div><\/div><div><\/div><div><\/div><div><\/div><div><\/div><div><\/div><div><\/div><div><\/div><\/div>"}; /* ]]> */ </script> <script type="text/javascript" id="better-reviews-js-extra"> /* <![CDATA[ */ var betterReviewsLoc = {"ajax_url":"https:\/\/lombardiasalute.com\/wp-admin\/admin-ajax.php","cp":"\/"}; /* ]]> */ </script> <script type="text/javascript" id="smart-lists-pack-pro-js-extra"> /* <![CDATA[ */ var bs_smart_lists_loc = {"translations":{"nav_next":"Next","nav_prev":"Prev","trans_x_of_y":"%1$s of %2$s","trans_page_x_of_y":"Page %1$s of %2$s"}}; /* ]]> */ </script> <script type="text/javascript" id="content-protector-pack-js-extra"> /* <![CDATA[ */ var cpp_loc = {"opt-1":[true,true],"opt-2":["",true,true,"",["ctrl_a","ctrl_c","ctrl_x","ctrl_v","ctrl_s","ctrl_u","ctrl_p","cmd_a","cmd_c","cmd_x","cmd_v","cmd_s","cmd_u","cmd_p","cmd_alt_i","ctrl_shift_i","cmd_alt_u"],true,true,["lombardiasalute.com"],""],"opt-3":["message","Iframe requests are blocked.",""]}; /* ]]> */ </script> <script type="text/javascript" id="publisher-js-extra"> /* <![CDATA[ */ var publisher_theme_global_loc = {"page":{"boxed":"boxed"},"header":{"style":"style-8","boxed":"stretched"},"ajax_url":"https:\/\/lombardiasalute.com\/wp-admin\/admin-ajax.php","loading":"<div class=\"bs-loading\"><div><\/div><div><\/div><div><\/div><div><\/div><div><\/div><div><\/div><div><\/div><div><\/div><div><\/div><\/div>","translations":{"tabs_all":"Tutti","tabs_more":"Di Pi\u00f9","lightbox_expand":"Expand the image","lightbox_close":"Close"},"lightbox":{"not_classes":""},"main_menu":{"more_menu":"enable"},"top_menu":{"more_menu":"enable"},"skyscraper":{"sticky_gap":30,"sticky":true,"position":""},"share":{"more":true},"refresh_googletagads":"1","get_locale":"it-IT","notification":{"subscribe_msg":"By clicking the subscribe button you will never miss the new articles!","subscribed_msg":"You're subscribed to notifications","subscribe_btn":"Subscribe","subscribed_btn":"Unsubscribe"}}; var publisher_theme_ajax_search_loc = {"ajax_url":"https:\/\/lombardiasalute.com\/wp-admin\/admin-ajax.php","previewMarkup":"<div class=\"ajax-search-results-wrapper ajax-search-no-product\">\n\t<div class=\"ajax-search-results\">\n\t\t<div class=\"ajax-ajax-posts-list\">\n\t\t\t<div class=\"ajax-posts-column\">\n\t\t\t\t<div class=\"clean-title heading-typo\">\n\t\t\t\t\t<span>Messaggi<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"posts-lists\" data-section-name=\"posts\"><\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t<div class=\"ajax-taxonomy-list\">\n\t\t\t<div class=\"ajax-categories-columns\">\n\t\t\t\t<div class=\"clean-title heading-typo\">\n\t\t\t\t\t<span>Categorie<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"posts-lists\" data-section-name=\"categories\"><\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"ajax-tags-columns\">\n\t\t\t\t<div class=\"clean-title heading-typo\">\n\t\t\t\t\t<span>tag<\/span>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"posts-lists\" data-section-name=\"tags\"><\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n","full_width":"0"}; /* ]]> */ </script> <div class="rh-cover noscroll " style="background-color: #31a069"> <span class="rh-close"></span> <div class="rh-panel rh-pm"> <div class="rh-p-h"> <span class="user-login"> <span class="user-avatar user-avatar-icon"><i class="fa fa-user-circle"></i></span> Sign in </span> </div> <div class="rh-p-b"> <div class="rh-c-m clearfix"></div> <form role="search" method="get" class="search-form" action="https://lombardiasalute.com"> <input type="search" class="search-field" placeholder="Ricerca..." value="" name="s" title="Cercare:" autocomplete="off"> <input type="submit" class="search-submit" value=""> </form> </div> </div> <div class="rh-panel rh-p-u"> <div class="rh-p-h"> <span class="rh-back-menu"><i></i></span> </div> <div class="rh-p-b"> <div id="form_27649_" class="bs-shortcode bs-login-shortcode "> <div class="bs-login bs-type-login" style="display:none"> <div class="bs-login-panel bs-login-sign-panel bs-current-login-panel"> <form name="loginform" action="https://lombardiasalute.com/wp-login.php" method="post"> <div class="login-header"> <span class="login-icon fa fa-user-circle main-color"></span> <p>Welcome, Login to your account.</p> </div> <div class="login-field login-username"> <input type="text" name="log" id="form_27649_user_login" class="input" value="" size="20" placeholder="Username or Email..." required/> </div> <div class="login-field login-password"> <input type="password" name="pwd" id="form_27649_user_pass" class="input" value="" size="20" placeholder="Password..." required/> </div> <div class="login-field"> <a href="https://lombardiasalute.com/wp-login.php?action=lostpassword&redirect_to=https%3A%2F%2Flombardiasalute.com%2F2021%2F11%2F24%2Fscoperto-un-gene-che-rende-regolare-il-ritmo-sonno-veglia-medicina%2F" class="go-reset-panel">Forget password?</a> <span class="login-remember"> <input class="remember-checkbox" name="rememberme" type="checkbox" id="form_27649_rememberme" value="forever" /> <label class="remember-label">Remember me</label> </span> </div> <div class="login-field login-submit"> <input type="submit" name="wp-submit" class="button-primary login-btn" value="Log In"/> <input type="hidden" name="redirect_to" value="https://lombardiasalute.com/2021/11/24/scoperto-un-gene-che-rende-regolare-il-ritmo-sonno-veglia-medicina/"/> </div> </form> </div> <div class="bs-login-panel bs-login-reset-panel"> <span class="go-login-panel"><i class="fa fa-angle-left"></i> Sign in</span> <div class="bs-login-reset-panel-inner"> <div class="login-header"> <span class="login-icon fa fa-support"></span> <p>Recover your password.</p> <p>A password will be e-mailed to you.</p> </div> <form name="lostpasswordform" id="form_27649_lostpasswordform" action="https://lombardiasalute.com/wp-login.php?action=lostpassword" method="post"> <div class="login-field reset-username"> <input type="text" name="user_login" class="input" value="" placeholder="Username or Email..." required/> </div> <div class="login-field reset-submit"> <input type="hidden" name="redirect_to" value=""/> <input type="submit" name="wp-submit" class="login-btn" value="Send My Password"/> </div> </form> </div> </div> </div> </div> </div> </div> </div> <script type="text/javascript" src="https://lombardiasalute.com/wp-content/plugins/simple-weather/js/vue.min.js" id="vue-js-js"></script> <script type="text/javascript" src="https://lombardiasalute.com/wp-content/plugins/simple-weather/js/vue-resource.min.js" id="vue-resource-js"></script> <script type="text/javascript" src="https://lombardiasalute.com/wp-content/plugins/simple-weather/js/moment.min.js" id="moment-js-js"></script> <script type="text/javascript" id="simple-weather-main-js-extra"> /* <![CDATA[ */ var SimpleWeather = {"rest_route":"https:\/\/lombardiasalute.com\/wp-json\/","locale":{"firstDay":1,"months":["Gennaio","Febbraio","Marzo","Aprile","Maggio","Giugno","Luglio","Agosto","Settembre","Ottobre","Novembre","Dicembre"],"monthsShort":["Gen","Feb","Mar","Apr","Mag","Giu","Lug","Ago","Set","Ott","Nov","Dic"],"weekdays":["domenica","luned\u00ec","marted\u00ec","mercoled\u00ec","gioved\u00ec","venerd\u00ec","sabato"],"weekdaysShort":["Dom","Lun","Mar","Mer","Gio","Ven","Sab"],"weekdaysMin":["D","L","M","M","G","V","S"],"gmtOffset":0},"settings":{"console_log":true}}; var SimpleWeatherAtts = []; var SimpleWeatherFeeds = []; /* ]]> */ </script> <script type="text/javascript" src="https://lombardiasalute.com/wp-content/plugins/simple-weather/js/simple-weather.js?ver=4.1.1" id="simple-weather-main-js"></script> <script type="text/javascript" src="https://cdn.onesignal.com/sdks/OneSignalSDK.js?ver=6.4.4' async='async" id="remote_sdk-js"></script> <script type="text/javascript" src="https://lombardiasalute.com/wp-content/plugins/better-adsmanager/js/advertising.min.js?ver=1.19.2" id="better-advertising-js"></script> <script type="text/javascript" async="async" src="https://lombardiasalute.com/wp-content/bs-booster-cache/588eab31ce2b0cc89d077bd012a4cccb.js?ver=6.4.4" id="bs-booster-js"></script> <script> var giu=function(a){"use strict";return{init:function(){0==giu.ads_state()&&giu.blocked_ads_fallback()},ads_state:function(){return void 0!==window.better_ads_adblock},blocked_ads_fallback:function(){var e=[];a(".giu-container").each(function(){if("image"==a(this).data("type"))return 0;e.push({element_id:a(this).attr("id"),ad_id:a(this).data("adid")})}),e.length<1||jQuery.ajax({url:'https://lombardiasalute.com/wp-admin/admin-ajax.php',type:"POST",data:{action:"better_ads_manager_blocked_fallback",ads:e},success:function(e){var t=JSON.parse(e);a.each(t.ads,function(e,t){a("#"+t.element_id).html(t.code)})}})}}}(jQuery);jQuery(document).ready(function(){giu.init()}); </script>  <script> var disqus_shortname = 'now-live-news'; (function () { var s = document.createElement('script'); s.async = true; s.type = 'text/javascript'; s.src = '//' + disqus_shortname + '.disqus.com/count.js'; (document.getElementsByTagName('HEAD')[0] || document.getElementsByTagName('BODY')[0]).appendChild(s); }()); //<script> (function(){ var disqus_shortname = 'now-live-news'; function beforeLoad(e,$wrapper, $this) { var $prevEl = jQuery('#disqus_thread'); if($prevEl.length === 0) { return; } $prevEl.removeAttr('id'); $prevEl.addClass('disqus_thread_prev'); } function appendDisqusScript(e,$wrapper, res) { if( typeof DISQUS === 'object' && DISQUS.reset ) { var info = res && res.info ? res.info : {}; jQuery(".disqus_thread_prev").each(function(){ var $prevEl = jQuery(this), $respond = $prevEl.closest('.comments-template'), $link = $respond.parent().find('.ajaxified-comments-container'); $link.show(); $link.children().show(); $respond.remove(); }); DISQUS.reset({ reload: true, config: function () { this.page.identifier = info.post_id; this.page.url = info.permalink; this.page.title = info.title; } }); } else { var dsq = document.createElement('script'); dsq.type = 'text/javascript'; dsq.async = true; dsq.src = '//' + disqus_shortname + '.disqus.com/embed.js'; (document.getElementsByTagName('head')[0] || document.getElementsByTagName('body')[0]).appendChild(dsq); } }; appendDisqusScript(); })(); </script>  </body> </html><script src="/cdn-cgi/scripts/7d0fa10a/cloudflare-static/rocket-loader.min.js" data-cf-settings="d5922a1935ee267ddee49beb-|49" defer></script><script data-cfasync="false" src="/cdn-cgi/scripts/5c5dd728/cloudflare-static/email-decode.min.js"></script>