Irbm-Merck al lavoro su nuovo farmaco anti-Covid aerosol – Medicina

By On Nov 29, 2021

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(ANSA) – ROMA, 29 NOV – L’azienda di biotecnologie Irbm di
Pomezia è al lavoro in collaborazione con l’azienda farmaceutica
Merck per la messa a punto di un nuovo farmaco anti-Covid in
formulazione aerosol o iniettabile, utilizzando una piattaforma
valida per l’adattamento alle varianti emergenti. Lo ha
affermato all’ANSA il direttore scientifico della Irbm, Carlo
Toniatti, a margine del congresso ‘Panorama Diabete’ organizzato
dalla Società italiana di diabetologia (Sid). “Gli studi
definitivi sulla fattibilità sono attesi entro il 2023”. È
inoltre “in corso un progetto di ricerca interna Irbm – ha
annunciato – su una nuova pillola orale anti-Covid”.

Il programma di ricerca Irbm per una nuova pillola
anti-Covid, ha spiegato Toniatti, “è incentrato sullo sviluppo
di una molecola in grado di inibire una delle proteine
essenziali per la replicazione del virus, diversa dalla proteina
Spike”. Infatti, ha chiarito, “la proteina Spike è sulla
superficie del virus Sars-CoV-2 ma lo stesso virus per
replicarsi, una volta all’interno dell’organismo ospite, ha
bisogno di varie proteine ‘interne’ che non sono colpite dai
vaccini attuali. Si tratta, dunque, di proteina che servono a
far replicare il virus, ma diverse dalla Spike”. L’obiettivo, ha
concluso, “è dunque quello di inibire tali proteine interne in
modo che il virus non possa replicarsi una volta presente nelle
cellule dell’organismo ospite”. Gli studi, ha concluso Toniatti,
“sono iniziati ed i dati definitivi sulla fattibilità sono
attesi per il 2023”. (ANSA).

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