Tumori:1,5 mln a ricercatore Italia per studio nuove terapie – Medicina

By On Nov 23, 2022

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(ANSA) – PERUGIA, 22 NOV – Marco Gargaro, ricercatore del
Dipartimento di Medicina e chirurgia dell’Università degli Studi
di Perugia, è risultato vincitore dell’Erc Starting Grant
ottenendo un finanziamento di 1.5 milioni di euro con il
progetto di ricerca “React-Dc, Breaking oncometabolites dynamics
for next-generation dendritic cells tumor immunotherapy” per
soluzioni terapeutiche innovative nella lotta ai tumori.

“Nonostante gli enormi progressi in campo oncologico soltanto
il 20-30% dei pazienti trattati con gli attuali approcci
immuno-terapici risponde a queste terapie” spiega Gargaro in una
nota dell’Ateneo. L’obiettivo del progetto React-Dc, dunque,
prevede l’identificazione di nuovi target farmacologici e lo
sviluppo di strategie terapeutiche innovative per potenziare la
capacità anti-tumorale delle cellule dendritiche. In
particolare, attraverso l’intelligenza artificiale e piattaforme
immuno-farmacologiche integrate, sarà possibile identificare
nuovi oncometaboliti come biomarcatori delle risposte
anti-tumorali. Inoltre, attraverso l’uso dell’ingegneria
genetica, saranno sviluppati nuovi approcci terapeutici
personalizzati e di precisione per ripristinare l’attività
anti-tumorale delle cellule dendritiche. Secondo l’Università i
risultati derivanti da questo progetto consentiranno dunque lo
sviluppo di trattamenti farmacologici più efficaci e meno
invasivi. (ANSA).

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